http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2423968-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99f4d329c880bb8c71dc36d897205a9d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate | 2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb3cbb8e2196747a28920500891e411e |
| publicationDate | 2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2423968-C1 |
| titleOfInvention | Method of obtaining micronised powder of organic medicinal substance with increased rate of solubility and bioavailability |
| abstract | FIELD: medicine, pharmaceutics. n SUBSTANCE: method lies in the following: initial organic medicinal substance and auxiliary volatile substance are simultaneously evaporated in gaseous medium, which has vacuum 10 2 - 10 -1 Pa. Obtained vapours of medicinal substance and auxiliary volatile substance are co-condensed respectively with rates 10 14 -5·10 17 molec/sec·cm 2 and 3·10 14 - 10 18 molec/sec·cm 2 respectively on precipitation surface with temperature from -196 to -50°C. Surface of precipitation is inclined at angle 10-90° relative to bisector of angle, formed by vectors of components precipitation and constituting 5-170°. When processes of co-condensation are over, temperature of precipitation surface is brought to temperature of surrounding medium with simultaneous removal from co-condensate of auxiliary volatile substance by pump-down in vacuum, process of pumping down auxiliary volatile substance is performed with heating precipitation surface to temperature which does not exceed 70°C, with further bringing temperature of precipitation surface to temperature of surrounding medium. n EFFECT: invention ensures one-stage method of obtaining micronised powders of organic medicinal substances with increased rate of solubility and bioavailability. n 2 cl, 4 dwg, 5 ex |
| priorityDate | 2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.