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filingDate 2006-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_117ea1bd30064cc03def2f609449f559
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publicationDate 2011-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2422835-C2
titleOfInvention Whole blood thrombine activity test
abstract FIELD: medicine. n SUBSTANCE: for thrombin production measurement, a layer of said sample contacts with a fluorogenic substratum of thrombin where the thickness of said layer is 0.05 to 5 mm, while the surface area is 10 to 500 mm 2 . Further, the thrombin production environment in said sample is provided. It is followed by measuring the fluorescence emitted from the layer surface by a fluorescent group released by the fluorescent substratum as a result of an enzymatic action of produced thrombin on said fluorogenic substratum. Besides, the invention ensures a kit for measuring the thrombin activity in the sample. n EFFECT: higher measuring accuracy. n 29 cl, 12 dwg, 5 ex
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