| abstract |
FIELD: medicine. n SUBSTANCE: tissue samples of an tumour and perifocal regions are recovered from the preparation removed intraoperatively. They are analysed for the contents of prolactin and testosterone by radioimmunoassay. If the prolactin concentration is 692.0 ng/g of tissue, and the testosterone concentration is 48.0 ng/g of tissue in the tumour, while the testosterone concentration is 42.0 ng/g of tissue in the perifocal region, developing hepatic metastases are expected in 3 months. If the prolactin concentration is 160-390 ng/g of tissue, and the testosterone concentration is 20-40 ng/g of tissue in the tumour, while the testosterone concentration is 24-26 ng/g of tissue in the perifocal region, developing metastases are expected in 29-43 months. n EFFECT: application of the method allows predicting developing metastases in patients suffering rectal cancer at a stage of primary surgical treatment that gives the chance to group the high-risk patients with rapid developing metastases for the purpose of well-timed adequate medical actions to be taken. n 2 ex, 1 tbl |