http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2420519-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fe99648570b368124a223fe6a34c6ca |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2006-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acb72da0c4545c4eec4a0bee43504585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c2155dfd645cd09c1b5326633d23b49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_572a385189022477452d8f6e6383f7f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f27494a83caf6e00c3fcfbd1490e72fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecd5eec63a9fd37c24f72b4b50d59423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8573d2a41c3fc3c36a0a662ef2c6e4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d443beb7fbf412da15eab7d782eb854b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6de3219eaeef208d2f3dc43a6cf9a5c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6502b9beef41ae04fe9a31ee7f685c43 |
| publicationDate | 2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2420519-C2 |
| titleOfInvention | Pyrimidine amide compounds as pgds inhibitors |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to a compound of formula , where R 1 represents aryl, heteroaryl or (C 5 -C 6 )-cycloalkyl, each of which has an optional substitute halogen or (C 1 -C 6 )-alkyl; R 2 represents hydrogen or (C 1 -C 4 )-alkyl; R 3 represents -P(=O)-(alkoxy) 2 or Y 1 Y 2 N-SO 2 -, cycloalkyl, aryl, heteroaryl, heterocyclyl, cycloalkenyl, each of which has an optional substitute: halogen, hydroxy, carboxy, Y 1 Y 2 N-, Y 1 Y 2 NC(=O)-, Y 1 Y 2 N-SO 2 , R 7 -SO 2 -NR 6 -, R 7 -C(=O)-NR 6 -, or alkyl, alkoxy, alkoxycarbonyl, each of which has an optional substitute halogen, -P(=O)-(alkoxy) 2 , Y 1 Y 2 NC(=O)-, Y 1 Y 2 N-SO 2 -, R 7 -SO 2 -NR 6 -, aryl or heteroaryl and when R 3 is cycloalkyl, cycloalkenyl, heterocyclyl, it also optionally substituted by oxo; L 1 represents a bond or (C 1 -C 6 )-alkylene, which is optionally substituted by -P(=O)-(alkoxy) 2 ; R 4 , R 5 and R 6 are hydrogen, R 7 represents alkyl; both Y 1 and Y 2 independently is hydrogen, alkyl which has an optional substitute: hydroxy, amino, alkylamino, dialkylamino, alkoxy, cycloalkyl, or Y 1 and Y 2 together with nitrogen atom whereto attached form heterocyclyl which optionally contains one more heteroatoms selected from oxygen, nitrogen or sulphur where heterocyclyl has an optional substitute alkyl or oxo; provided when L 1 represents a bond, R 3 is not optionally substituted by phenyl, optionally substituted by naphthyl, optionally substituted by benzoimidazolyl, optionally substituted by benzothiazolyl or optionally substituted by tetrazolyl; or to its pharmaceutically acceptable salt, and also to a pharmaceutical composition including a compound of formula I. n EFFECT: there are produced and described new compounds which can be effective in treating allergic or inflammatory disorders, particularly such disorders, as allergic rhinitis, asthma or chronic obstructive pulmonary disease. n 25 cl, 118 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2655914-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2655914-C9 |
| priorityDate | 2005-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 716.