| abstract |
FIELD: medicine. n SUBSTANCE: method of isolating myeloid-like cells of bone marrow is realised by processing bone marrow cells with antibodies against CD44 ( hyaluronic acid receptor), against CD11b or against both, and with application of flow cytometry. After that, positive selection from them of cells, expressing CD44 and/or CD11b, is carried out. Isolated myeloid-like cells of bone marrow can be transformed with the gene, coding therapeutically applicable protein, to deliver the gene into the retina. n EFFECT: obtained cells possess favourable vasculotrophic and neurotrophic activity, when introduced intraocularly into and eye of a mammal. n 21 cl, 46 dwg, 3 tbl, 17 ex |