| abstract |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention, in particular, relates to method of obtaining compound of formula where R, R1 R2, R3 and PG are determined in description, or its salt, which lies in reaction of formula I compound with reagent, selected, for instance, from group including hydrohalic acid, thionylhydrogenide, PX*3, POX*3, PX*5, POX*5, where X* represents halogen, combination of triphenylphosphine and halogen and active derivative of organic sulfonic acid. ^ EFFECT: elaboration of novel method, novel method stages and novel intermediate compounds for synthesis of pharmaceutically active compounds, in particular, rennin inhibitors, such as aliskiren. ^ 63 cl, 11 ex |