| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to novel substituted 2-quinolyloxazoles of formula (I) or pharmaceutically acceptable salts thereof, having PDE4 inhibiting properties, a pharmaceutical composition based on said compounds and use thereof to prepare a medicinal agent which inhibits inflammatory cell recruitment in respiratory tracts. , where is , X is O, R 1 is alkyl, R 3 and R 4 are independently selected from H, R 5 and R 6 are independently selected from a group comprising H, alkyl, hydroxyalkyl, t equals 1 or 2. Values of substitutes R 7 -R 11 , R 13 are given in the formula of invention. n EFFECT: high efficiency of using the composition. n 24 cl, 1 dwg, 64 ex |