| abstract |
FIELD: medicine, pharmaceutics. n SUBSTANCE: invention refers to pharmaceutical industry and medicine, and concerns a new gel-containing pharmaceutical composition for local and external application for treating the diseases of skin, soft tissues, oral tissues, including periodontium, and arthropathies of various aetiology. The pharmaceutical composition contains an active substance and a carrier glycerohydrogel of solvated complexes of silicon and titanium glycerates of the following structure 2Si(C 3 H 7 O 3 ) 4 ·Ti(C 3 H 7 O 3 ) 4 ·x C 3 H 8 O 3 ·y H 2 O, where 9≤x≤30, 60≤y≤120 in the following proportions, wt %: the active substance 0.5-7.0, the carrier - the rest. The active drug substance can be represented with antibacterial preparations of fluoroquinolones (e.g. pefloxacin, ciprofloxacin), metronidazole, antibiotics (e.g. lincomycin), nonsteroidal anti-inflammatoy drugs (e.g. sodium diclofenac), hormonal preparations (e.g. dexamethasone), vitamins (e.g. aecol), antiseptics (e.g. chlorhexidine biguconate), anaesthetic drugs (e.g. lidocaine hydrochloride), or other biologically active substances. n EFFECT: improved efficacy of the drug. n 2 cl, 7 ex |