| abstract |
FIELD: medicine. n SUBSTANCE: invention refers to medicine, and concerns a bioengineered structure for bony defect closure and osteogenesis which represents a hybrid implant comprising a porous polytetrafluorethylene membrane with a M-Ca-P-C-O-N or M-Ca-C-O-N doped multifunction, biocompatible, non-resorbed coating MBNC, where M is a metal chosen from a line including Ti, Zr, Hf, Nb, Ta, with autogenous or allogenic stromal cells recovered from fatty tissue or bone marrow passed on the surface thereof. n EFFECT: invention provides reliable degree of cell population attachment to the surface of the bioengineered structure with high cell culture adhesion and growth. n 4 cl, 2 dwg |