http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2415155-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0386387c72578255f11416b50e644519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F222-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F2-18 |
| filingDate | 2010-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_965264f9add45af98d1edce2543867c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8acbc2e3130da8211304a159e7d1dcfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b1ae9da303bca84a068ce057355f5c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbaae8520d503130539e73912b8b0630 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd0c97b861d1731df9d64b0286e16fc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90fc183f11c804abebe76511b78b0ef9 |
| publicationDate | 2011-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2415155-C1 |
| titleOfInvention | Method for synthesis of cross-linked polymeric plasma sorbent, molercularly imprinted with uric acid |
| abstract | FIELD: chemistry. ^ SUBSTANCE: present invention relates to production of cross-linked polymeric plasma sorbent based on dimethacrylate ethylene glycol, which is molecularly imprinted with uric acid. Described is a method for synthesis of a cross-linked polymeric plasma sorbent which is molecularly imprinted with uric acid, involving suspension radical copolymerisation of dimethacrylate ethylene glycol and dimethyl aminoethyl methacrylate, in the presence of uric acid salts, a dinitryl-2-iso-bis-isobutyric acid initiator, characterised by that the said reagents are dissolved in glycerine; copolymerisation is carried out while stirring the mixture of reagents in an inert atmosphere and heating on a water bath at 70C for 2 hours; the reaction is carried out in weight ratio dimethacrylate ethylene glycol : dimethyl aminoethyl methacrylate equal to 99-98:1-2; comonomers: solvent (glycerine) equal to 17-20:83-80 wt %; the uric acid salts used are salts with diethyl amine and guanidine in ratio glycerine: uric acid salt equal to 96:4 wt %; uric acid is removed from the cross-linked polymer through extraction with a mixture of 0.1n HCl and ethanol (1:1) for 5 hours. ^ EFFECT: obtaining low-swelling and pH stable cross-linked polymers with imprints which are complementary to uric acid. ^ 1 cl, 1 tbl, 4 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2608743-C2 |
| priorityDate | 2010-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.