http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2414473-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-424 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 |
filingDate | 2006-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f688875a61f3fe96565c63bbe57df92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7b02213ef7867c61697464f58026f4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19e816a6b505917e8163d54894f8e887 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b9775b61757f8ffb83192ea49e94878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45ca5cc6a9c3ce7d5b20c826a17467c1 |
publicationDate | 2011-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2414473-C2 |
titleOfInvention | Azolopyridin-2-one derivatives as lipase and phospholipase inhibitors |
abstract | FIELD: chemistry. n SUBSTANCE: invention relates to compounds of general formula I and to their physiologically compatible salts. In general formula I , X denotes identical or different groups =C(-R)- or =N-, wherein at least one =C(-R-)- is substituted by =N-; Y is -O-; R denotes identical or different hydrogen, halogen, (C 1 -C 6 )-alkyl; R1 denoes (C 4 -C 16 -alkyl, ( C1 -C 4 )-alkylene-(C 6 -C 10 )-aryl, (C 1 -C 4 )-alkylene-(C 3 -C 12 )-cycloalkyl, (C 9 -C 10 )-bicyclic ring, wherein the aryl can be singly or multiply substituted with (C 1 -C 6 )-alkyl; R2 denotes hydrogen; or R1 and R2 together with the nitrogen atom which it is bonded form a monocyclic, saturated 6-member ring in which separate members of the ring system can be substituted with -CHR4-; R4 denotes (C 1 -C 6 )-alkyl. The invention also relates to a pharmaceutical composition having inhibiting action on endothelial lipase (EL) and containing one or more compounds of formula I, to use of the disclosed compounds to prepare a medicinal agent and to methods of producing compounds of formula I. n EFFECT: high effectiveness of derivatives. n 11 cl, 20 ex |
priorityDate | 2005-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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