| abstract |
FIELD: chemistry. ^ SUBSTANCE: invention relates to a compound of formula (1) or salts thereof, (1), where R1 denotes a hydrogen atom or a C1-6alkyl group; R2 denotes a hydrogen atom, R3 denotes a hydrogen atom or a C1-6alkyl group when R4 and R5 denote hydrogen atoms, R6 denotes a hydrogen atom or a cyano group, or in >C(R6) C(R5)(R4) - denotes a double bond, R4 and R6 are absent, and R5 denotes a hydrogen atom; or R4 denotes a hydrogen atom and R5 denotes a hydroxy group or a halogen atom, R6 denotes a hydrogen atom or a cyano group, R7 denotes one or two substitutes selected from a group comprising a hydrogen atom, a halogen atom, a nitro group and C1-6alkoxy group, A denotes a 5-member or a 6-member non-aromatic heterocyclic ring which contains one sulphur atom (the sulphur atom can form an oxide), W denotes an oxo group, two hydrogen atoms, two fluorine atoms or a combination of a hydrogen atom and a hydroxy group, and X denotes an oxygen atom or a sulphur atom. ^ EFFECT: medicinal agent based on these compounds have inhibitory action on production of prostaglandin E2 and can be used in medicine to treat urological diseases. ^ 5 cl, 7 tbl, 69 ex |