| abstract |
FIELD: medicine. ^ SUBSTANCE: claimed is application of conjugate of heparin with lysine and ibuprofen of formula as anti-inflammatory medication with anticoagulant, antitumour and antimetastatic activity. Conjugate of heparin with lysine and ibuprofen, where R=So3H/Ac (30:70). ^ EFFECT: conjugate possesses anti-inflammatory activity, which is 1,4 times higher than ibuprofen activity, anticoagulant activity is comparable with pharmacopeia heparin, its antitumour activity being comparable with that of doxorubicin, cyclophosphane, vincristine, prednisolone with demonstration of antimetastatic activity. ^ 6 tbl |