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grantDate 2010-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2010-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2405040-C2
titleOfInvention Method for producing l-amino acid
abstract FIELD: medicine. ^ SUBSTANCE: method involves cultivation of a microorganism of Enterobacteriaceae family capable to produce L-amino acid, in a nutrient medium, and recovery of said L-amino acid from the culture liquid. Said microorganism is modified by the introduction of a DNA fragment including a pho regulon promoter and a structural gene coding L-amino acid biosynthesis enzyme ligated behind the promoter in such a manner that gene expression is controlled by said promoter. And the activity of L-amino acid biosynthesis enzyme increases in the promoter gene expression with phosphorus concentration in the medium is such that induction of said promoter is observed. ^ EFFECT: invention allows producing L-amino acids with high efficiency. ^ 12 cl, 4 dwg, 7 tbl, 2 ex
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