| abstract |
FIELD: medicine. n SUBSTANCE: invention refers to a polymer derivative of cytidine antimetabolite of formula (1) which can be used as an antineoplastic drug: (1), where R is hydrogen or alkyl; A is hydrogen, acyl or alkoxycarbonyl; m is within 3 to 200; n is within 5 to 2000; X is a residue of cytidine antimetabolite, hydroxyl or a hydrophobic substitute, and X means a residue of cytidine antimetabolite in amount 3-100 % m, hydroxyl in amount 0-95 % m and the hydrophobic substitute in amount 0-80 % m. n EFFECT: preparation of new antineoplastic compounds. n 8 cl, 5 ex, 4 tbl |