abstract |
FIELD: medicine. n SUBSTANCE: invention relates to novel hemin derivatives of general formula I n n n n where R 1 =R 2 and represent β-alanyl histamine or γ-gutamyl histamine, or β-alanyl histidine, or R 1 represents γ-gutamyl histamine; Y represents CI - ; Me represents Fe n+ , where n=2, 3; and where hemin carboxyl group can be modified with methyl or other C 1-8 ether their pharmaceutically acceptable salts; method of their obtaining and pharmaceutical compositions. n EFFECT: hemin derivatives of general formula I can be used as artificial nucleases, means, possessing peroxidase activity, catalysts of methyl linoleate oxidation and disinfecting, antiseptic composition, possessing virucidal activity. n 9 cl, 1 dwg, 7 tbl, 10 ex |