http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2403870-C9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b260fac036a7acddf9d848ce4250ea2 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-00 |
| filingDate | 2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a2afac64e3726b8fe4269bb05260d8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3acc9d89e34558c98d196ffd70d46f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5c14e553785fc8c3c7c8fc552d78d40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ea5b89984687e9a35150f037876e1a2 |
| publicationDate | 2011-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2403870-C9 |
| titleOfInvention | Method of bone resorption to remodelling analysis |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to medicine, namely to biochemistry, surgery and dentistry. The bone resorption to remodeling analysis is based on the biochemical blood examination. An the blood coefficient K 1 is calculated by formula: K 1 =[(PTH:A)+(TNF-α:B)+(IL-1β:C)]:3, where PTH is the parathyroid hormone concentration (pg/ml) in the patients, A is the same value in healthy individuals, TNF-α is the level of tumor necrosis factor -α (pg/ml) in the patients, B is the same value in healthy individuals, IL-1β is the interleukin-1β concentration (pg/ml) in the patients, C is the same value in healthy individuals to derive the blood coefficient K 2 by formula: K 2 =[(calcitonin: D) + (osteocalcin: E)]:2, where the calcitonin concentration (ng/ml) in the patients, D is the same value in healthy individuals, the osteocalcin level (ng/ml) in the patients, E is the same value in healthy individuals. Then the bone metabolism control coefficient (BMCC) is calculated by formula BMCC=K 1 :K 2 , and the higher BMCC than 1.17, the more intensive resorption prevails over remodelling; and the lower BMCC than 0.83, the more intensive remodelling prevails over resorption. n EFFECT: method allows high accuracy detection of prevalence of resorption or remodelling intensity in the bone stock metabolism control in practically healthy individuals (monitoring) and in pathology cased for the purpose of diagnosis, assessment and therapeutic prognosis. n 5 tbl, 3 dwg, 2 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2715283-C1 |
| priorityDate | 2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.