http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2403257-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fe99648570b368124a223fe6a34c6ca |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 |
| filingDate | 2005-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d190fedea2514d3f1347c885879a267a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81166595217d74b0f2be6d571e5f69cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fad271b95652f2e4783804ffc11fc2c |
| publicationDate | 2010-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2403257-C2 |
| titleOfInvention | SUBSTITUTED AMIDES OF THIENOPYRROLECARBOXYLIC ACID, AMIDES OF PYRROLE THIAZOLE CARBOXYLIC ACID AND RELATIVE ANALOGUES AS CASEIN KINASE Iε INHIBITORS |
| abstract | FIELD: medicine, pharmaceutics. n SUBSTANCE: claimed invention relates to compounds of formula (I) and formula (II), their tautomers and pharmaceutically acceptable salts. In formula (I) and in formula (II), X - S; R 1 - H; R 2 - NR 5 R 6 ; R 3 - 5-6-member heteroaryl with 1 heteroatom, selected from N and S, or phenyl, optionally substituted with one or two substituents, selected from halogen, amino, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -halogenalkyl and C 1 -C 6 -halogenalkoxy; R 4 - H, C 1 -C 6 alkyl, C 1 -C 6 alkoxy or XR 3 , where X and R 3 are determined above; R 5 - H; R 6 - H; L - N or CR 7 , where R 7 - H; M - S. Invention also relates to pharmaceutical composition, containing as active component invention compound, to method of inhibiting activity of caseinkinase lε and to method of obtaining compounds of formula (I) or formula (II). n EFFECT: compounds of claimed invention possess properties of casein kinase lε inhibitors. n 13 cl, 5 tbl, 44 ex |
| priorityDate | 2004-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 388.