http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2403045-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18b6c41eb01733269d27aa06ac89721f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d39cd13f4daf84bcfd6f0f6f212bc861 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 2008-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_599c0084ca2d063bde0818932324836c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c4d1a1b263b86199d0ed4c6617ad2a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b7901a0d8171bee041332bd5701cab7 |
| publicationDate | 2010-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2403045-C2 |
| titleOfInvention | Method of manufacturing anti-depression medication in form of mianserin hydrochloride-based tablets, preparation obtained by said method, and its crystal structure |
| abstract | FIELD: medicine, pharmaceutics. n SUBSTANCE: invention relates to field of pharmaceutical chemistry, namely to manufacturing anti-depression mianserin hydrochloride-base medication. Medication is made in form of tablets and contains mianserin hydrochloride, calcium diphosphatedihydrate, potato starch, methylcellulose, aerosil, magnesium stearate with film coating on the basis of hydroxypropylmethylcellulose. In accordance with method of manufacturing, mianserin hydrochloride, calcium diphosphatedihydrate, 60% of potato starch mass and 40% of aerosol mass are mixed, after which mass is moisturised with methylcellulose, preliminarily dissolved in water and heated to temperature 45-55°C, obtained wet mass is dried to residual humidity 2.5-3.0%, granulated through sieve with hole diametre 1-1.5 mm and is mixed with the remaining 40% of starch and 60% of aerosol, magnesium stearate is added, by means of pressing obtained are tablets-nuclei, onto which film coating based on hydroxypropylmethylcellulose is applied. Also determined is crystal structure of preparation. n EFFECT: invention ensures obtaining of tablets with sufficient strength and time of dissolution within 15-20 minutes. n 6 cl, 3 dwg, 12 tbl |
| priorityDate | 2008-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.