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publicationDate 2010-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2402605-C1
titleOfInvention STRAIN OF HYBRID CULTIVATED CELLS OF ANIMALS Mus Musculus, PRODUCING MONOCLONAL ANTIBODIES, SPECIFIC TO PEPTIDE, WHICH POSSESSES APOPTOTIC ACTIVITY WITH RESPECT TO CANCER CELLS
abstract FIELD: medicine. ^ SUBSTANCE: described is strain of hybrid cultivated cells of animals Mus. Musculus RIM9 - producer of monoclonal antibodies, specific to peptide of human milk - lactaptin and its recombinant analogues, which possess apoptotic activity with respect to human cancer cells. Invention allows to obtain monoclonal antibodies, recognising general linear antigen determinant of recombinant and natural lactaptin. ^ EFFECT: possibility to elaborate sensitive and specific test-systems for detecting lactaptin, antibodies to it and for isolation of lactaptin from human milk by method of affinity chromatography. ^ 2 tbl, 4 ex
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