http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2401303-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78b3ef18597e67f4ee1dec7b91740f01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate | 2009-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d718fcd042225b80b577a1b01f1abf0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b220f46657db0f12b30da333fb716422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7795f3872cdf41ea6112502c7216460c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_029e259f597f0748a0c5913e0eacdd19 |
| publicationDate | 2010-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2401303-C1 |
| titleOfInvention | Animal mus musculus hybrid cell g10b6 clone l-producer of monoclonal diphtheria toxin antibodies |
| abstract | FIELD: medicine. ^ SUBSTANCE: there is presented a new G10B6 hybrid cell clone producing monoclonal diphtheria toxin antibody in the environment of cell culture and abdominal cavity of syngeneic animals. The clone is produced by the fusion of mouse myeloma SP-2/0 cells with popliteal lymph node cells of BALB/c mice immunised with a commercial preparation of diphtheria toxin (manufactured by State Institution Gamaleya's Epidemiology and Microbiology Research Institure) in posterior pads. A fusing agent is polyethylene glycol of molecular weight 4000. Hybridoma selection has been performed on Dulbecco modified Eagle's medium with bovine foetal serum and hypoxantine-aminopterin-thymidine added. Hybridoma synthesizes monoclonal antibodies specifically reacting with diphtheria toxin. The antibody titre is 1:10000 1:20000 in the culture fluid, and 1:1000000 in ascitic. Antibodies can be used for designing immunobiological systems of diphtheria toxin detection exceeding available analogues in sensitivity, specificity and reproducibility. ^ EFFECT: invention can be used for creation of the diagnostic test-systems exceeding available analogues in sensitivity, specificity and reproducibility. ^ 2 dwg, 4 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2616289-C2 |
| priorityDate | 2009-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.