http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2401299-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78b3ef18597e67f4ee1dec7b91740f01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate | 2009-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9364458118526879f4575bb75e5e3c83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b220f46657db0f12b30da333fb716422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d718fcd042225b80b577a1b01f1abf0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7795f3872cdf41ea6112502c7216460c |
| publicationDate | 2010-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2401299-C1 |
| titleOfInvention | Animal mus musculus hybrid cell clone l-producer of monoclonal cholera toxin antibodies |
| abstract | FIELD: medicine. n SUBSTANCE: there is produced a new CT-B1/F8 hybrid cell clone producing monoclonal cholera toxin antibody (MCAB) in the environment of cell culture and abdominal cavity of syngeneic animals. The clone is produced by the fusion of mouse myeloma SP-2/0 cells with popliteal lymph node cells of BALB/c mice immunised with a commercial preparation of cholera toxin (SIGMA) in posterior pads. A fusing agent is polyethylene glycol of molecular weight 4000. Hybridoma selection has been performed on Dulbecco modified Eagle's medium with bovine foetal serum and hypoxantine-aminopterin-thymidine added. Hybridoma synthesises MCAB specifically interacting with cholera toxin and not interacting with thermolabile E.coli toxin. The antibody titre reaches 1:20000 in the cultural fluid, 1:2000000 in ascitic. n EFFECT: antibodies can be used for designing immunobiological systems of cholera toxin detection exceeding available analogues in sensitivity. n 2 dwg, 4 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2528099-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2583306-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2590587-C1 |
| priorityDate | 2009-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.