abstract |
FIELD: medicine. n SUBSTANCE: invention refers to medicine and concerns methods and compositions for improving effectiveness of antibody for medical application with using the compounds potentiating NK-cells. Substance of the invention covers a method of treating a disease and a pharmaceutical composition for treating a disease brought on or exacerbated partially by the cells which can be considered as targets and which can be eliminated by antibody for medical application, involving introduction to a patient of the first antibody blocking an inhibiting NK-cell receptor chosen of group: KIR2DL1, KIR2DL2, KIR2DL3 and NKG2A and then introductions of antibody for medical application. n EFFECT: advantage of the invention consists in higher clinical effectiveness. n 40 cl, 2 ex, 1 tbl, 4 dwg |