http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2395582-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_039d3c0bc946de8cabe72739c350a1ec |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_512edf1d7165a8eb91b9a66ac0955542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad116aad0dbaacc415a94db66043a277 |
| publicationDate | 2010-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2395582-C2 |
| titleOfInvention | METHOD OF SPLITTING POLYPEPTIDES USING PROTEASE OmpT VERSION |
| abstract | FIELD: chemistry; biochemistry. n SUBSTANCE: invention relates to biotechnology, particularly genetic engineering and can be used in biomedical industry. The invention discloses a method of obtaining a target peptide by splitting a polypeptide or a fused protein using a version of protease OmpT with substitution of the amino acid in position 97, where the amino acid is selected from alanine, leucine, phenylalanine, methionine, serine, threonine, cysteine, asparagine, glutamine, glutaminic acid and histidine, on a site whose structure is characterised by general formula Pn…P2-P1-P1'-P2'…Pn', where P1 is asparagine or lysine, P2 and P2' are an amino acid which is not glutamic or asparagic acid, and P1' is alanine, valine, isoleucine, phenylalanine, methionine, serine, threonine, cysteine, tyrosine or asparagine. n EFFECT: use of the invention can enable efficient and specific isolation of therapeutic peptides with any type of N-terminal sequence. n 22 cl, 3 tbl, 20 dwg, 18 ex |
| priorityDate | 2003-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.