| abstract |
FIELD: chemistry. n SUBSTANCE: present invention relates to compounds characterised by formula I, and their use as sodium and/or calcium channel modulators when treating a wide range of diseases, including cardio-vascular, inflammatory, eye, urological, metabolic and gastro-intestinal diseases, as sell as a method of producing formula I compounds and pharmaceutical compositions based on formula I compounds. , where m equals 1-3, X is -CH 2 -, O, S or NR 6 ; R 1 is a possibly substituted alkyl, alkenyl or alkynyl, phenyl, benzyl, phenoxy or naphthyl; R 2 , R 3 represent hydrogen, alkyl, halogen, trifluoromethyl, hydroxy or alkoxy; R 4 , R 5 , R 6 represent hydrogen or alkyl. n EFFECT: obtaining of novel biologically active compounds and pharmaceutical compositions based on the said compounds. n 7 cl, 13 ex |