http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2393159-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c90d4c9eb6f4837513dd1a4c6906f811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc0a660b94e5a16da4df469e7951e6f8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2008-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6f8fe693a5ca0cd063a49b2d5201523 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d091d90fa24958d7c920f69b17ad532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a575e601380f594212e9e60d0992b6d2 |
| publicationDate | 2010-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2393159-C1 |
| titleOfInvention | SUBSTITUTED 2-ALKYLSULFANYL-3-SULFONYL-PYRAZOLO[1,5-a]PYRIMIDINES, SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS, METHODS OF PRODUCING AND USING SAID COMPOUNDS |
| abstract | FIELD: chemistry. n SUBSTANCE: present invention relates to novel substituted 2-alkylsulfanyl-3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines of general formula 1, their pharmaceutically acceptable salts and/or hydrates having serotonin 5-HT 6 receptor antagonist properties. In general formula 1 , R 1 and R 3 independently denote optionally identical C 1 -C 3 alkyl, and R 2 is a -(CH 2 ) n X group or R 1 and R 3 independently denote different substitutes selected from C 1 -C 3 alkyl or a -(CH 2 ) n X group, and R 2 is a hydrogen atom or C 1 -C 3 alkyl; R 4 is C 1 -C 3 alkyl; R i 5 is a hydrogen atom, one or two identical or different halogen atoms, C 1 -C 3 alkyl; equals 0, 1 or 2; n equals 0, 1, 2 or 3; X is a carboxyl CO 2 H, C 1 -C 3 alkyloxycarbonyl, aminocarbonyl CONR 6 R 7 or amino group NR 6 R 7 ; except compounds in which R 3 is a -(CH 2 ) n X group, where X is an amino group NR 6 R 7 and n equals 0; R 6 and R 7 are optionally identical and denote a hydrogen atom, optionally substituted C 1 -C 5 alkyl or R 6 and R 7 together with the nitrogen atom with which they are bonded form an optionally substituted 6-member azaheterocyclyl containing 1-2 nitrogen atoms in the ring, where the substitute is selected from C 1 -C 3 alkyl. n EFFECT: obtaining compounds which can be used in treating diseases of the central nervous system during prevention or treatment of cognitive disorders, neurodegenerative diseases, psychiatric disorders, have anxiolytic and nootropic effect and can be used to prevent and treat anxiety disorders and enhance mental capacity. n 25 cl, 2 tbl, 12 ex |
| priorityDate | 2008-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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