http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2392947-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_214d3fa8c87231ff88e1497c5ea9fe3b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2008-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5b124ec2d48f14aa382260f4c7b4a1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c681a983d69be25b59e4f8d250c4350 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9aebe01ad9803050718bc266938aba6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3f8bb2c6d5d09529dbe339e6ac7523e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e32d433c1935bf504e339f59567e5a60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_586c3a1993bbfda34ac51f3b849b5c39 |
| publicationDate | 2010-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2392947-C1 |
| titleOfInvention | Method for preparing cell transplantation material in myelosuppression |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to experimental medicine and concerns preparation of a cell transplantation material in myelosuppression. That is ensured by subcutaneous introduction to a laboratory animal of a recombinant granulocytic colony-stimulating factor (G-CSF) in dosage 125 mcg/kg once a day for 3 days. It is combined with intraperitoneal introduction of hyaluronidase in dosage 1000 SU/kg once a day for 2 days. Then mononuclear leukocyte fraction of peripheral blood is prepared, placed in a balanced nutrient medium containing 10 -8 mol/ml of D-glucuronic acid, and incubated for 2 hours. n EFFECT: introduction of G-CSF and hyaluronidase in the developed dosage and regimen, in combination with incubation with D-glucuronic acid added provides higher therapeutic activity of the graft due to mononuclear growth in peripheral blood and better engrafting ability. n 1 ex, 4 tbl |
| priorityDate | 2008-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.