http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2389501-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13 |
| filingDate | 2004-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20d195a62071b3b7d93bbb9516fdef74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9948ff18fa918dc806b3b53dc0cd78bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3880d13c02a625d7b5a9c9b7eda3798b |
| publicationDate | 2010-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2389501-C2 |
| titleOfInvention | Application of modified cyclosporins for treating hcv induced diseases |
| abstract | FIELD: medicine, pharmaceutics. n SUBSTANCE: there is offered application of cyclosporine for preparing a pharmaceutical composition for prevention or treatment of hepatitis C related infections or HCV induced disorders, where cyclosporine (a) is bound with human recombinant cyclophilin with a bound constant (BC) is at least 0.7, where the BC represents a decimal logarithm of the relation of IC 50 cyclosporine and IC 50 cyclosporine A in simultaneous experiment for estimating by competitive assay ELISA; and (b) exhibits activity in a lymphocyte reaction in a mixed culture 5% and less in comparison with the activity of cyclosporine A, where cyclosporine is [MeIle]cyclosporine or a compound of formula (versions). n EFFECT: prepared compounds inhibit HCV and in treatment do not suppress immune system, can be used in combination with other anti-HCV agents. n 12 cl, 2 dwg |
| priorityDate | 2003-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 403.