abstract |
FIELD: chemistry. n SUBSTANCE: method involves asymmetric reduction of (E)-2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-ylidene)ethyleneamine, catalytic reduction of the obtained product at temperature ranging from 40 to 100°C and pH ranging from 3 to 9, propionylation of the obtained (S)-2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine, and then crystallisation from the reaction mixture. n EFFECT: obtaining optically active amine derivatives of high purity with high output and prevention of formation of by-products. n 6 cl, 1 tbl, 3 ex |