| abstract |
FIELD: microbiology. n SUBSTANCE: invention represents plasmid vector for transfer of DNA, which comprises sequence coding various fragments of oncoprotein p185 neu , which are able to induce immune response in respect to tumors, which hyperexpress p185 neu . Invention is also related to pharmaceutical composition on the basis of vector for prophylactics or treatment of patients with risk of development of p185 neu -positive tumors, or patients with primary tumors, metastases or relapses of p185 neu -positive tumors. n EFFECT: invention makes it possible to increase efficiency of prophylactics or treatment of patients with risk of development of p185 neu -positive tumors, or patients with primary tumors, metastases or relapses of p185 neu -positive tumors. n 10 cl, 14 dwg, 2 tbl, 2 ex |