| abstract |
FIELD: microbiology. n SUBSTANCE: invention may be used for considerable reduction of variations in produce of recombinant proteins, which occur in process of cells cultivation with application of various batches of commercially available soy-bean hydrolysate. Medium is produced for cells cultivation, which does not contain animal proteins, by means of complementing of mediums, which do not contain animal proteins, with soy-bean hydrolysate and additionally with biogenic amine in the range of 1-18 mg/l. Produced medium is used to produce recombinant proteins by means of cultivation of according cells. n EFFECT: invention makes it possible to reduce contagiousness of product, and also to increase efficiency of growth and productivity of cells. n 12 cl, 9 dwg, 12 ex |