abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to compounds of formula n or n n or to their pharmaceutically acceptable salts, where ring A, R 2 , R 3 , R 4 and X are as defined in the description. The disclosed compounds are useful as 11βHSD1 inhibitor. The invention also relates to a pharmaceutical composition, an agent for treating or preventing pathology related to glucocorticoids, a 11βHSD1 inhibitor containing the disclosed compound or its pharmaceutically acceptable salt, and use of the disclosed compounds. n EFFECT: compounds are highly effective. n 40 cl, 48 tbl, 191 ex |