abstract |
FIELD: chemistry. ^ SUBSTANCE: present invention relates to steroids with (11)-[4-(aza-aryl)phenyl] substitutes which modulate progesterone receptors, or pharmaceutically acceptable salts and/or hydrated form, and/or prodrug thereof. ^ EFFECT: compounds exhibit combined activity profile of PR agonist and PR antagonist which makes them suitable for contraception and treating gynaecological disorders. ^ 30 cl, 28 ex, 1 tbl |