http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2381229-C2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10efc646a4dd605c2f09c493718f5b81 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4738 |
filingDate | 2007-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3714e361be1ddd6f4b9e1032922a7112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c95c241d0838f7eaaf9bb41c86b460bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a584ec899a581f6322157b4d6c7ad48e |
publicationDate | 2010-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2381229-C2 |
titleOfInvention | 11b-(HET)ARYL-2,3,611b-TETRAHYDROOXAZOLO[2',3':2,1]PYRROLO[3,4-b]QUINOLIN-5,11-DIONES AND SYNTHESIS METHOD THEREOF |
abstract | FIELD: chemistry. n SUBSTANCE: invention relates to 11b-(het)aryl-2,3,6,11b-tetrahydrooxazolo[2' , 3':2,1]pyrrolo [3,4-b]quinolin-5,11-diones with general formula 1 R 1 =Ar, Het; R 2 =H, Alk, OAlk, halogen; R 3 - H, Alk, OAlk, halogen; R 4 =H, Alk, OAlk, halogen and to a synthesis method which involves reacting initial 3-(het)aroyl-4-oxo-1,4-dihydro-2-quinolincarboxylate with monoethanolamine in ratio 1:1 in methanol, ethanol, tetrahydrofuran, toluene, dioxane while heating in the presence or absence of acetic acid for 2-24 hours (control using thin-layer chromatography). n EFFECT: formula 1 compounds have potential for use as low-toxicity substances with biological activity, for example antimicrobial, antiviral and anticonvulsant; method of producing formula 1 compounds is easy to implement, safe, does not require special conditions, allows for obtaining substances which can not be produced using other methods. n 2 cl, 10 ex |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2668969-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2711968-C1 |
priorityDate | 2007-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.