| abstract |
FIELD: chemistry. ^ SUBSTANCE: invention relates to novel nonsteroid synthetic derivatives with the following structures or their pharmaceutically acceptable salts: ^ , , , ^ , ^ or ^ , which are capable of modulating the androgen receptor. ^ EFFECT: invention relates to pharmaceutical compositions containing said derivatives and use thereof to make nonsteroid medicinal agents for treating and/or preventing conditions or diseases such as prostate hyperplasia, prostate cancer, hirsutism, severe hormone-dependant alopecia or acne etc, resulting from antagonistic activity towards the androgen receptor. ^ 6 cl, 5 dwg, 3 tbl,12 ex |