http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2372337-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6042509de7544921c96de43b9da1438 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-54 |
| filingDate | 2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53d27560c19d88ff220ef7175a6122e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca4a92db892f1b1b92737ca18d2bf9d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f752b6e7f1d915b91d80917f6157cd6 |
| publicationDate | 2009-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2372337-C2 |
| titleOfInvention | Dihydropyridine derivatives |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to dihydropyridine derivatives with general formula , or their pharmaceutically acceptable salts, where R 1 is C 1-6 alkyl or phenyl, C 1-5 heteroaryl, both optionally substituted with one or more substitutes, chosen from hydroxy, amino, halogen, nitro, cyano; R 2 , R 3 are independently C 1-4 alkyl, C 1-4 alkoxy group, C 2-4 alkenyloxy group, C 3-4 alkynyloxy group, halogen; R 4 is C 1-6 alkyl, C 3-6 cycloalkyl, C 3-6 cycloalkylC 1-4 alkyl, C 6-10 aryl, C 6-10 arylC 1-4 alkyl, C 1-9 heteroaryl, where the (hetero)aryl group is optionally substituted with one or more substitutes, chosen from hydroxy, amino, halogen, nitro, trifluoromethyl, cyano, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, C 1-4 alkoxy group, C 1-4 (di)alkylamino group, and, if R 4 is a phenyl, additionally from C 1-4 alkylthio group, C 1-4 alkylsulphonyl, R 5 -oxycarbonyl, R 5 -carbonyl or R 5 ,R 6 -aminocarbonyl; X is SO 2 , CH 2 , C(O) or X is absent, where X is CH 2 , R 4 can additionally represent R 5 -oxycarbonyl, or R 5 -carbonyl; R 5 , R 6 are independently H, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, C 3-6 cycloakyl, C 3-6 cycloalylC 1-4 alkyl, C 2-6 heterocycloalkyl, C 2-6 heterocycloalkylC 1-4 alkyl, C 1-4 alkoxycarbonylC 1-4 alkyl, C 1-4 (di)alkylaminocarbonylC 1-4 alkyl or C 6-10 arylaminocarbonylC 1-4 alkyl, C 1-9 heteroarylaminocarbonylC 1-4 alkyl, C 6-10 aryl, C 1-9 heteroaryl, C 6-10 arylC 1-4 alkyl, C 1-9 heteroarylC 1-4 alkyl, where the (hetero)aryl group is optionally substituted with one or more substitutes, chosen from hydroxy, amino, halogen, nitro, trifluoromethyl, cyano, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, C 1-4 alkoxy group, C 1-4 (di)alkylamino group or R 5 , R 6 in R 5 , R 6 - aminocarbonyl group can be bonded to a C 2-6 heterocycloalkyl ring, as well as to a pharmaceutical composition with antagonistic activity towards FSH receptor and to use of these compounds for making medicinal agents. n EFFECT: compounds which are suitable for treating fertility disorders are obtained and described. n 11 cl, 33 ex |
| priorityDate | 2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 314.