http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2368611-C1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04
filingDate 2008-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2009-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e1765bb1970edb84a702fed908e6a80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7e3f657028cd550114d5e2411d489bf
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publicationDate 2009-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2368611-C1
titleOfInvention METHOD OF OBTAINING DERIVATIVES OF N-ACETYL-4-HYDROXY-2METHYL-5-(5-METHYLFUR-2-YL)-1H-BENZO[g]INDOLE
abstract FIELD: chemistry. n SUBSTANCE: invention relates to a method of obtaining derivatives of N-acetyl-4-hydroxy-2-methyl-5-(5-methylfur-2-yl)-1H-benzo[g]indole with general formula I: Ia-d lla-d I, lla R=H; R 1 =H, I, llb R=Cl; R 1 =H, I, llc R=Br; R 1 =H, I, Ild R-OCH 3 ; I R 1 =OCH 3 , characterised by that formation of a furyl-substituted benzo[g]indole basic structure results from opening and re-closing of the annelated furan ring in the corresponding 2-alkyl-4-N,N-diacetylamino-9-(5-methyl-2-furyl)naphthofurans lla-d while boiling them for 1 minute in a 30% hydrogen chloride solution in ethanol. n EFFECT: method reduces resin formation of the reaction mass, allows for obtaining desired products with high output and widens the range of derivatives, which can be used in obtaining anti-inflammatory compounds. n 1 cl, 3 tbl, 5 ex
priorityDate 2008-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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