| abstract |
FIELD: medicine. n SUBSTANCE: invention covers phosphinic acid derivatives of formula I which can be used for treating Alzheimer's disease, and methods for making thereof. where R 1 stands for aryl or heteroaryl; R 2 stands for alkyl or phenyl; R 3 stands for hydrogen, alkyl or phenyl; R 4 stands for alkyl, cycloalkyl, phenyl, pyridyl, tolyl, trifluorobutyl, tetrafluorobutyl, heptafluorobutyl, hydroxyphenyl, methoxyphenyl, methylpyridinyl. n EFFECT: production of new biologically active substances. n 11 cl, 6 ex |