http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2361222-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64b698c37801340a494f8bd80b18ba4f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2008-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2ec47911085905f1e9ede9eaa9c5195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7dd7bac185c58aad2561706d6556516 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d76cf11852c0382b75d317db38b6cdcf |
| publicationDate | 2009-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2361222-C1 |
| titleOfInvention | Breast cancer outcome prediction method |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to medicine area, namely to oncology. Breast cancer (BC) outcome prediction method involves biochemical examination of tumour tissue for activity of aromatase, 2,4-oestrogenhydroxylase and glutathione-S-transferase. If activity of aromatase is less than 20 fmole/mg of protein per hour, activity of 2,4-oestrogenhydroxylases is more than 230 pmole/mg of protein per hour regardless activity of glutathione-B-transferase, high probability of recurrence is predicted. If activity of glutathione-S-transferase is less than 40 mkmol/mg of protein per minute without changes in other indicators, high probability of distant metastases are predicted. If activity of aromatase is more than 20 fmol/mg of protein per hour, activity of 2,4-oestrogenhydroxylases is less than 230 pmol/mg of protein per hour, activity of glutathione-S-transferase is more than 40 mkmol/mg of protein per minute, favourable clinical outcome of the disease in recurrence development and/or remote metastases is predicted. n EFFECT: high-accuracy and informative prediction of disease progressing in the form of tumour recurrences and/or metastases within first 2 years in BC patients after radical surgical treatment. n 2 ex, 3 dwg |
| priorityDate | 2008-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.