| abstract |
FIELD: chemistry. n SUBSTANCE: invention refers to practically pure polymorphic forms of A and B N-[({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridine-1-yl)phenyl] ethyl}-amino)carbonyl]-4-methylbenzolsulphone-amide, to pharmaceutical compositions containing specified polymorphic forms, and also to their application and application of pharmaceutical compositions containing them. Additionally, the invention concerns method of pain management, therapy of inflammation, osteoarthritis or rheumatoid arthritis, as involving introduction of saif polymorphic forms A and B. n EFFECT: new crystal forms of N-[({2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridine-1-yl)phenyl] ethyl}-amino)carbonyl]-4-methylbenzolsulphone-amide are the most stable of the identified forms. n 14 cl, 2 tbl, 12 ex, 6 dwg |