http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2356560-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1202ebfd5892b47f9df6dd4a1835609 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d036c93ac2ce16a1ce3f3696a4ebbfed http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0239f74582c365deb9dba732cab8ce6f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
| filingDate | 2007-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e5bd7767c96093c3f999e6762b54bd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8836e28e99925935aa5a31e2ca5fd89d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4d735e43da7e849a4ab8bfec721a3e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ae8742f3132f9feefa85f99289d1387 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ca824f695f351659b4c8d6e3d27fbdf |
| publicationDate | 2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2356560-C1 |
| titleOfInvention | Ceruloplasmin recovery method |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to medicine, namely to ceruloplasmin recovery, and can be used in making enzyme blood-plasma medicines. The disclosed method includes dissolution of feed stock in acetate buffer, enzyme sorption in an ion-exchange reactor with functional DEAE group, elution and following purification. Said ion-exchange reactor with functional DEAE group represents a sorbent on fixed styroldivinylbenzene matrix with co-graft DEAE group. And in purification, at first the dissolved enzyme is treated with a solvent-detergent mixture. Then the treated enzyme is immobilised on sulphopropylcation sorbent, washed in acetate buffer containing sodium chloride. The purified enzyme is eluted, while the feed stock is dissolved in acetate solution. The enzyme is sorbed in the ion-exchange reactor wherein as such sorbent on fixed styroldivinylbenzene matrix with co-graft DEAE group is applied. The enzyme is eluted and purified. In purification, the enzyme solution is treated with a solvent-detergent mixture, immobilised on sulphopropylcation sorbent, washed in acetate buffer containing sodium chloride. The purified enzyme is eluted. n EFFECT: method ensures virus safety of recovered medical product ceruloplasmin and allows improving end product yield. n 9 cl, 2 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2488403-C1 |
| priorityDate | 2007-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.