http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2353622-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2be8e1ef21191a7500ea89d41849061 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 |
filingDate | 2004-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b8086d2f89588a16ec1177b472102e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4265b12bdb0fc8478cf3a08eb556e2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3602626eb67cdbc4111f34acc44a85ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6581a536cd1fcfecf45caedbdca57657 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_868527a3cc1f1e39eb1ebd8a8b525eb7 |
publicationDate | 2009-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2353622-C2 |
titleOfInvention | Novel fusidic acid derivatives |
abstract | FIELD: chemistry. n SUBSTANCE: claimed invention relates to novel fusidic acid derivatives of general formula [I], where X represents halogen, trifluoromethyl, C 1 -C 7 alkyl, substituted with phenyl, C 2 -C 9 alkenyl, optionally substituted with C 1 -C 7 alkyl, halogen or phenyl, phenyl, optionally substituted with one or two similar or different substituents, selected from group consisting of halogen, C 1 -C 7 alkyl, C 2 -C 9 alkenyl, phenyl, C 1 -C 6 alkoxy, nitro, C 1 -C 6 alkyltio, trifluoromethyl and cyano; or X represents naphtyl; Y and Z both represent hydrogen or together with bond C-17/C-20 form double bond between C-17 and C-20 or together represent methylene and form cyclopropane ring in combination with C-17 and C-20; A represents O, S or S(O); B represents C 1-6 alkyl, C 2-6 alkenyl, C 1-6 acyl, phenyl or benzoyl, where C 1-6 alkyl is optionally substituted with one or more halogens, hydroxy, C 2-6 alkenyl, phenyl, C 1-4 heteroaryl or C 1-6 alkoxy; Q 1 represents -(CHOH)-, or -(CHW)-, where W represents halogen or azido; Q 2 represents -(CHOH)-; to their pharmaceutically acceptable salts and easily hydrolysed esters and to pharmaceutical compositions, including said derivatives, as well as to their application in therapy. n EFFECT: application in therapy. n 31 cl, 127 ex, 5 tbl |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2746947-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2477316-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2726122-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2726196-C1 |
priorityDate | 2003-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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