| abstract |
FIELD: chemistry; pharmacy. n SUBSTANCE: invention claims novel [1,2,4]triazolo[1,5-a]pyrimidine-2-ylurea derivatives of the general formula (1), or their pharmaceutically acceptable salts: [formula 1] , where Ar is optionally substituted phenyl group, dihydrobenzofuranyl or thiophenyl group. X is O. R is group of formula (2)-(6) or , where values of Cy and R 4 -R 12 radicals are given in the claim, and medicine containing these compounds. n EFFECT: obtaining compounds with immunosuppressive or immune tolerance inducing effect, which can be applied in medicine. n 14 cl, 16 tbl, 333 ex |