abstract |
FIELD: medicine, microbiology. n SUBSTANCE: invention concerns biotechnology. It is described bispecific antibody which binds also the factor of blood coagulation IX or the activated factor of blood coagulation IX, and the factor of blood coagulation X, and functionally replaces the factor of blood coagulation VIII or the activated factor of blood coagulation VIII which strengthens enzymatic reaction. The pharmaceutical composition containing the described antibody is revealed. The present invention can be used as an alternative agent for functional replacement of cofactor which strengthens enzymatic reaction. n EFFECT: creation of bispecific antibody which can replace functional proteins, strengthens enzymatic reaction. n 14 cl, 18 dwg, 37 ex |