http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2333246-C2
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 |
filingDate | 2001-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2008-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2008-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2333246-C2 |
titleOfInvention | Photochemical internalisation for molecule transportation to cytosol |
abstract | FIELD: chemistry. n SUBSTANCE: invention concerns molecular biology and can be applied in medicine. One variant of molecule introduction into a cell cytosol involves contact of transported molecule to the cell after its incubation with photosensitiser and irradiation. The other variant of the method involves contact of transported molecule to the cell after its incubation with photosensitiser either during or after irradiation. Methods of disease, disorder or infection treatment or prevention, gene therapy, cancer treatment and immune response stimulation are developed on the basis of this method. Transport cell of therapeutically tolerable molecule and a cell presenting antigen molecule are also obtained by the said method. n EFFECT: reduced level of photochemical damage of transported molecule and possibility of wide variability of the transported molecule introduction time relative to photosensitiser-containing cell irradiation time. n 53 cl, 26 dwg, 1 tbl, 24 ex |
priorityDate | 2000-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 277.