| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56c437cd855edfef225f383522dc50f9 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49 |
| filingDate |
2006-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d87c7564e25327bc3ed6b31c9620a42d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dfccb28d4e91b14e2cc775aa5ce52c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cd8d2d09ece49870cf43ce04a4535dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb7adbe5cfa8be24807befc947e4e9e6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eb6cb033c345f3f8525dd3b3eb598d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_286f3cac6cf0d4fb0ab8a2aa9f97ed91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39d50425bff60949c64e678b74a9f910
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e5c00dfd4e482ab89d79e17d0e4d9bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_418aec05ed8bc30efddfae580540ab04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd6af3b3e664eac08ee6371ad74179f2 |
| publicationDate |
2008-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2332667-C1 |
| titleOfInvention |
Method of granulocytopenia-stimulating effect evaluation for pharmacological substances |
| abstract |
FIELD: medicine. n SUBSTANCE: invention concerns experimental medicine, particularly hematology and pharmacology. The claimed method involves registration of absolute quantity of hematosis granulocyte shoot cells - neutrophils - in peripheral blood of experimental animals (mice) after hematosis hypoplasia emulation by a single administration of cytostatic agent in maximum endurable dose (MED) (cyclophosphane or 5-fluorouracil) before and after administration of a substance under test. Reliable criterion of granulocytopenia-stimulating effect of administrated pharmacological substance is increase in neutrophil quantity by 150% or more. n EFFECT: simplification of definition method for granulocytopenia-stimulating effect of pharmacological substances and extension of its applicability. n 3 ex, 3 tbl |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2488890-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2444023-C1 |
| priorityDate |
2006-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |