| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to the new aminopyridine derivative of the formula (I-A) , where R 2 and R 3 are independently selected from hydrogen, C 1 -C 6 -alkyl; R 5 represents the group of formula or, or where R 9 , R 10 , R 11 , R 12 and R 13 independently represent hydrogen, halogen, cyanogen, C 1 -C 6 -alkoxy; R 14 and R 15 independently have values, determined above for R 9 -R 13 , to the pharmaceutical composition on the basis of the said connections, possessing antagonistic activity with respect to mGluR5 receptors. The invention also relates to the method of treating the disorders of the central nervous system as well as other disorders modulated by receptors mGluR5 and to the application of connections of the formula I, for preparing medicine. n EFFECT: obtaining new connections and a pharmaceutical composition on their basis, for the purposes of treating disorders of the central nervous system. n 13 cl, 13 ex |