abstract |
FIELD: medicine; pharmacology. n SUBSTANCE: invention refers to creation and application of aerosol spray compositions for treatment of diseases or disorders requiring lowering of cell proliferation and/or induction of cell apoptosis, such as neoplastic, autoimmune, viral diseases. Agent contains as active substance vitamin E based composition of structural formula , where R 1 is carboxylic acid; R 2 and R 3 are hydrogen or R 4 ; R 4 is methyl, and R 5 is alkyl; or where R 1 is hydrogen or carboxylic acid; R 2 and R 3 are hydrogen or R 4 ; R 4 is methyl, and R 5 is alkenyl. n EFFECT: improved delivery of specified composition by inhalation with intensified antiproliferation activity. n 59 cl, 17 dwg, 6 tbl, 35 ex |