http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2327475-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c083b03ef212717d22c2fe74b601c9fd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| filingDate | 2006-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_702163df513847edd5df833fd5a4e16f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dde8b1faf65cce9e7d473641599b7f2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9831d5aa3edce2d6c5a7e106ae30776a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a6fd04b0bb8fc6ba67a7e968bcd923d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71e4df37de730188bca7c2750b3c963b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43ef4ebe9527280ad2bccf56a2e14de8 |
| publicationDate | 2008-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2327475-C1 |
| titleOfInvention | Method of production of immonuactive polypeptides/peptides having immunomodulating properties |
| abstract | FIELD: medicine; immunology. n SUBSTANCE: method implies that animals' thymus, e.g. sea animals' thymus, is defatted and connective tissue cleaned, milled, lyophilised, degreased with liquid CO 2 , hydrated in isotonic phosphate buffer at pH 7.2-7.4, sediment is removed by centrifugation, supernatant is collected and warmed up at 80°C during 10-15 min, centrifugated, supernatant is collected and pH is reduced to 4.0-4.2, deposited with ammonium sulphate, formed sediment is removed by centrifugation, dissolved in tris-HCl buffer, pH 8.0-8.2, ammonium sulphate is removed on column with Sephadex G-15, material of column outer content is, lyophilised, dissolved in 0.01 M tris-HCl, buffer containing 0.14 M NaCl, pH 8.0-8.2, gel- chromatographed on column with Sephadex G-50, end product is collected by molecular weight 500 to 25000 dalton, lyophilised, dissolved in bidistilled water and desalted on column with Sephadex G-15, end product produced in column free content is lyophilised. n EFFECT: method provides higher product yield and storage stability. n 1 tbl, 4 ex |
| priorityDate | 2006-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.