http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2326942-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05c50822fc6cef61985b2ba0dfb8164d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 |
| filingDate | 2007-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47aa7cca2a21fd0680dcdd0c0c5befcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe73334bc964ad040ca73b86c33ec82d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0143c2c75c38816852ed9dc4ed31cb10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2376efd3b85fa95caa98ce1d24d2498c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd1a8d90bd1491ab0f82cdf3f69190d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88662c1ed66135735a515f6a98a90605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36f06b69b903c9ca310ae53490ed6cea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c13a53f06b011b62fca10c3af825ba8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d30f167e5e6b4cb1f28e23d8b85d0b7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81724506c60b1893e04bae48f163ed7c |
| publicationDate | 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2326942-C1 |
| titleOfInvention | Method of preparation of recombinant birds virus for vaccination and genetic therapy |
| abstract | FIELD: technological processes; veterinary medicine. n SUBSTANCE: on the basis of genomic DNA of birds adenovirus CELO two plasmids are designed, one of which contains its left fragment (1-20028 bps), which includes expressing cassette under control of own main late promoter of adenovirus MLP, and the other contains the right fragment of genome CELO (17,390-43,804 bps) with zone that is homologous to nucleotide sequence of the first plasmid for performance of recombination, and also with deletion in 3,787 bps for increase of packing capacity of adenovirus CELO. Expressing cassette is cloned in the area of deletion, which consists of exogenic promoter that provides high level of expression in eukaryotic cells, polylinkers for cloning of one or more target genes and signal of polyadenylation. Homologous recombination between designed plasmids is performed in the culture of cells of leghorn rooster hepatoma (LMH), which provides preparation of recombinant birds adenovirus CELO. For cloning in expressing cassettes genes of cytokines, growth factors, antigens and oncosuppressors of human being, birds and microorganisms are used, both taken separately and in certain combinations for achievement of required genetic therapeutic effect or high level of immunisation. n EFFECT: creation of genetically engineered recombinant vaccines of new generation and preparations for genetic therapy. n 32 cl, 4 dwg, 22 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108118034-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2528250-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108118034-A |
| priorityDate | 2007-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 759.